Nucleotides - Definition, Examples, Quiz, FAQ, Trivia
Discover how tiny molecules create DNA and RNA - the instructions for all living things!
What are Nucleotides?

Nucleotides are the tiny building blocks that make up DNA and RNA - the molecules that carry all the instructions for life! Think of them like letters in a genetic alphabet that spell out how living things grow and function.
Every nucleotide has three important parts: a nitrogenous base, a sugar molecule, and a phosphate group. When many nucleotides join together, they form long chains that create DNA and RNA.
Did You Know?
Your body contains about 3 billion nucleotides in each cell's DNA! That's enough to fill about 200 phone books with genetic information!
Parts of a Nucleotide

Each nucleotide is made of three special parts that work together:
Nitrogenous Base
The information-carrying part that forms genetic code letters: A, T, C, G in DNA or A, U, C, G in RNA
Pentose Sugar
A 5-carbon sugar that forms the backbone: deoxyribose in DNA and ribose in RNA
Phosphate Group
The connector that links nucleotides together to form chains
The nitrogenous bases come in two types:
Purines: Adenine (A) and Guanine (G) - these have two rings
Pyrimidines: Cytosine (C), Thymine (T) in DNA, Uracil (U) in RNA - these have one ring
Base Pairing Rule!
In DNA, Adenine (A) always pairs with Thymine (T), and Guanine (G) always pairs with Cytosine (C). This is called complementary base pairing!
Nucleotides in DNA & RNA

Nucleotides form both DNA and RNA, but with some important differences:
DNA Nucleotides
• Sugar: Deoxyribose
• Bases: A, T, C, G
• Structure: Double helix
• Function: Stores genetic information
RNA Nucleotides
• Sugar: Ribose
• Bases: A, U, C, G
• Structure: Single strand
• Function: Helps make proteins
The sequence of nucleotides in DNA forms genes, which are like recipes that tell cells how to make proteins. RNA acts as a messenger that carries these instructions to the protein-making machinery in cells.
Example: A DNA sequence might look like: A-T-T-G-C-A. This sequence would be transcribed into RNA as: A-U-U-G-C-A.
Nucleotide Quiz
Test your nucleotide knowledge with this quiz! Answer all 5 questions to see how much you've learned.
Frequently Asked Questions
Here are answers to some common questions about nucleotides:
Fun Nucleotide Trivia
Discover some amazing facts about nucleotides!
Tiny But Mighty
A single nucleotide is only about 0.33 nanometers wide. If you lined up all the nucleotides in your DNA end-to-end, they would stretch to the sun and back about 600 times!
Human Blueprint
Humans share about 99.9% of the same nucleotide sequence with each other. The 0.1% difference is what makes each person unique!
Animal Similarities
Humans share about 98% of their DNA nucleotide sequence with chimpanzees, 90% with cats, 85% with mice, and even 60% with bananas!
Speedy Reading
Your cells can read DNA nucleotides at an incredible speed! During protein synthesis, ribosomes can process about 6 nucleotides every second to build proteins.