Skip to main content
Skip to main content

What are Nucleotides?

Visual representation of nucleotides forming a DNA strand
Nucleotides linking together to form DNA

Nucleotides are the tiny building blocks that make up DNA and RNA - the molecules that carry all the instructions for life! Think of them like letters in a genetic alphabet that spell out how living things grow and function.

Every nucleotide has three important parts: a nitrogenous base, a sugar molecule, and a phosphate group. When many nucleotides join together, they form long chains that create DNA and RNA.

Parts of a Nucleotide

Diagram showing the three components of a nucleotide
The three parts of a nucleotide

Each nucleotide is made of three special parts that work together:

Nitrogenous Base

The information-carrying part that forms genetic code letters: A, T, C, G in DNA or A, U, C, G in RNA

Pentose Sugar

A 5-carbon sugar that forms the backbone: deoxyribose in DNA and ribose in RNA

Phosphate Group

The connector that links nucleotides together to form chains

The nitrogenous bases come in two types:

Purines: Adenine (A) and Guanine (G) - these have two rings
Pyrimidines: Cytosine (C), Thymine (T) in DNA, Uracil (U) in RNA - these have one ring

Nucleotides in DNA & RNA

Comparison of DNA and RNA structures showing nucleotide differences
DNA vs. RNA nucleotide structure differences

Nucleotides form both DNA and RNA, but with some important differences:

DNA Nucleotides

• Sugar: Deoxyribose
• Bases: A, T, C, G
• Structure: Double helix
• Function: Stores genetic information

RNA Nucleotides

• Sugar: Ribose
• Bases: A, U, C, G
• Structure: Single strand
• Function: Helps make proteins

The sequence of nucleotides in DNA forms genes, which are like recipes that tell cells how to make proteins. RNA acts as a messenger that carries these instructions to the protein-making machinery in cells.

Example: A DNA sequence might look like: A-T-T-G-C-A. This sequence would be transcribed into RNA as: A-U-U-G-C-A.

Nucleotide Quiz

Test your nucleotide knowledge with this quiz! Answer all 5 questions to see how much you've learned.

1. What are the three main parts of a nucleotide?
2. Which nitrogenous base is found in RNA but not in DNA?
3. What sugar is found in DNA nucleotides?
4. Which base pairs with Adenine in DNA?
5. What is the main function of nucleotides in DNA?

Frequently Asked Questions

Here are answers to some common questions about nucleotides:

Fun Nucleotide Trivia

Discover some amazing facts about nucleotides!

Related Resources

No resources found matching the criteria.

Copyright © 2025 Workybooks. Made with ♥ in California.