Endoplasmic Reticulum and Its Function — Reading Comprehension

The endoplasmic reticulum, or ER, is a large, maze-like structure inside the cell that helps make and move important materials. It stretches from the nucleus to other parts of the cell, acting like a highway system. There are two types of ER: rough ER and smooth ER, and each has a different job.

The rough endoplasmic reticulum is covered with ribosomes, which give it a bumpy appearance under a microscope. These ribosomes build proteins, and the rough ER helps fold and transport those proteins to other places in the cell. Some proteins are sent to the Golgi apparatus for packaging, while others are used right away by the cell.

The smooth endoplasmic reticulum does not have ribosomes, so it looks smooth. Instead of helping with proteins, it makes lipids, which are fats used in cell membranes and energy storage. The smooth ER also helps remove harmful substances from the cell, especially in liver cells.

Together, both types of ER help the cell stay organized and efficient. Without the ER, the cell would not be able to make or move the materials it needs to grow, repair damage, or stay healthy. Different cells have different amounts of rough and smooth ER depending on what they do. For example, cells that make lots of proteins have more rough ER, while cells that produce hormones or clean toxins may have more smooth ER.

Fun Fact: The endoplasmic reticulum is so large that it makes up more than half the total membrane in many cells!

What does the endoplasmic reticulum help the cell do?

What gives the rough ER its bumpy appearance?

What is the main job of the rough ER?

What does the smooth ER produce?

Which type of cell would likely have more smooth ER?

Where do some proteins go after leaving the rough ER?

What is the main idea of the passage?

What would happen if the ER didn’t work properly?