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What is a Genetic Mutation?

Illustration showing DNA structure with a mutation
Illustration showing DNA structure with a mutation

A genetic mutation is a change that happens in our DNA. DNA is like an instruction manual that tells our bodies how to grow and work. Sometimes, small changes happen in these instructions, and we call these changes mutations.

Think of DNA as a recipe for making cookies. If you change one ingredient in the recipe (like using salt instead of sugar), you'll get a very different cookie! Genetic mutations work similarly - they change the instructions that make us who we are.

Types of Genetic Mutations

There are several types of genetic mutations. The main types include:

1

Substitution

One DNA letter is replaced with another, like changing a word in a sentence

2

Insertion

Extra DNA is added where it shouldn't be, like adding an extra word

3

Deletion

Some DNA is removed, like deleting words from a sentence

4

Duplication

Part of the DNA is copied twice, like repeating words in a sentence

Some mutations are helpful, some are harmful, and many don't make any noticeable difference at all! Helpful mutations can help organisms adapt to their environment over time.

Examples of Genetic Mutations

Examples of genetic mutations in nature
Examples of genetic mutations in nature

Genetic mutations can create visible differences in living things. Here are some examples:

White Tigers

A mutation causes their white fur with dark stripes

Blue Eyes

A mutation thousands of years ago created blue eye color in humans

Antibiotic Resistance

Mutations can help bacteria survive medicines

Mutations can also cause genetic conditions like:
• Cystic fibrosis (affects lungs and digestion)
• Sickle cell anemia (affects red blood cells)
• Color blindness (affects color vision)

Some mutations provide benefits! For example, a mutation called CCR5-delta32 makes some people resistant to HIV infection.

Genetic Mutations Quiz

Test your knowledge about genetic mutations with this quiz! Answer all 5 questions to see how much you've learned.

1. What is a genetic mutation?
2. Which of these is NOT a type of genetic mutation?
3. What is an example of a helpful mutation?
4. Where do genetic mutations occur?
5. Which of these is an example of a visible mutation?

Frequently Asked Questions

Here are answers to some common questions about genetic mutations:

Fun Genetic Mutation Facts

Discover some amazing facts about genetic mutations!

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